The vision of VCS Foundation is ‘to prevent cancer and infectious disease through excellence in the provision of population health services supporting screening and vaccination’. In line with this vision, VCS Foundation pursued its charitable purposes in the last financial year through the activities of its three business units: VCS Pathology, VCS Population Health and VCS Digital Health. VCS Pathology has continued to support Australia’s National Cervical Screening Program (NCSP) through the provision of unparalleled high quality laboratory services and advice to health professionals. In 2018/19, VCS Pathology reported approximately 250,000 HPV tests across six different HPV testing platforms, making the laboratory one of the largest publicly-funded molecular, not just screening, laboratories in Australia. VCS Pathology was the first laboratory nationally to be accredited for self-collected samples as part of the renewed NCSP, improving the accessibility of Australian women to life-saving cervical screening tests. Our medical education unit provided health professionals with accredited training, education materials and telephone support. This included free education and training to GPs, nurses and aboriginal workers who each play important roles in promoting and undertaking screening pathways. This strong laboratory and medical expertise enables VCS Pathology to service underserved populations in Australia and around the world. VCS Pathology also continued into Phase Two of the Compass Trial, seeking to confirm that the HPV test is a superior screening method and assessing different ways of deciding which women need further investigation if they have a positive test. VCS Population Health and VCS Digital Health continued their leadership in the delivery of high quality population health services. Projects have included the Providing Access to Immunisation for Vulnerable Groups (PAIVnG) to facilitate the immunisation management of refugees and asylum seekers, a collaborative project with the Menzies to deliver a Plan of Action to improve the reporting of Indigenous status in HPV vaccination and cervical screening programs, and a new data and reporting services to support cancer screening in Victoria. The 2018/19 financial year saw the closure of the Victorian Cervical Cytology Registry after its transition to the National Cancer Screening Register in June 2019, and the National HPV Vaccination Program Register after the transition to the Australian Immunisation Register in 2018. Our Population Health team continued to provide the participant follow up function for the National Bowel Cancer Screening Program in Victoria. Our Digital Health team are working with the Jean Hailes Foundation to develop the digital platform underpinning the National Endometriosis Clinical and Scientific (NECST) Network, and the Victorian Government to implement an Immunisation System Replacement for local councils.