For over 35 years Menzies School of Health Research teams have worked closely with communities to ensure our research, education and training address fundamental health and development priorities. Menzies staff are also making discoveries that will make a positive impact on Indigenous Aboriginal and Torres Strait Islander Australians and tropical health, and will benefit all Australians and many others in our region. Key achievements and research projects in 2019 include: • Launching the new Otitis Media Guidelines app, an interactive tool to assist primary health care providers in the delivery of comprehensive, effective and appropriate care for Aboriginal and Torres Strait Islander people with otitis media (ear infections). • Developing the Ask the Specialist podcast – a cultural education podcast which features Larrakia, Tiwi and Yolŋu leaders answering questions from doctors about working with Aboriginal patients at Top End hospitals. • Establishing the Ramaciotti Regional and Remote Health Sciences Training Centre (Menzies-Ramaciotti Centre) which provides a pathway into the laboratory and health sector for regional and remote youth, with a focus on career development for Aboriginal and Torres Strait Islander youth.Our research directly informing national and international treatment guidelines and health policies for suicide prevention, kidney disease management, malaria, antimicrobial resistance (AMR) and paediatric respiratory health. • Commencing the fifth wave of the Aboriginal Birth Cohort (ABC) Study, Australia’s largest and longest running study of Aboriginal people. • Establishing an office in Timor-Leste, which will support testing and surveillance for antimicrobial resistance and health systems strengthening